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Getting the USB programming cable to work with a VM can be a hassle but my friend had it working on his Mac a while ago.
Altera quartus ii programmer manual#
This manual is designed for the novice Quartus II software user and provides an overview of the capabilities of the Quartus II software in programmable logic design. Another option is run it in a VM, I use Quartus II on Win7 but iirc it's native to nix and is well supported on Linux.